SCHEMBL25690727

SCHEMBL25690727

CC(C)(C)OP(=O)(OCOC(=O)CCC(=O)OCc1ccccc1)OC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.46
▸ MAPK1 P28482 2/20 0.46
▸ L3MBTL1 Q9Y468 2/20 0.46
▸ LMNA P02545 1/20 0.43
▸ NOTUM Q6P988 1/20 0.41
▸ TSHR P16473 1/20 0.41
▸ POLB P06746 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ FOLH1 Q04609 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ TDP1 Q9NUW8 2/20 0.40
▸ SLC6A2 P23975 1/20 0.40
▸ SLC6A3 Q01959 1/20 0.40
▸ GLA P06280 1/20 0.39
▸ CETP P11597 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30392722 0.95 ALDH1A1 (0.44) ALDH1A1MAPK1L3MBTL1LMNATSHR
SCHEMBL13654753 0.89 ALDH1A1 (0.46) ALDH1A1MAPK1L3MBTL1LMNATSHR
SCHEMBL25213014 0.87 ALDH1A1 (0.44) ALDH1A1MAPK1L3MBTL1LMNATSHR
SCHEMBL25257764 0.86 HTT (0.53) L3MBTL1LMNAKMT2AMEN1MAPT
SCHEMBL25575859 0.86 GLA (0.46) L3MBTL1LMNAKMT2AMEN1MAPT
SCHEMBL2984888 0.86 ALDH1A1 (0.49) ALDH1A1MAPK1L3MBTL1TSHRKMT2A
SCHEMBL25255619 0.85 ALOX5 (0.37) ALDH1A1MAPK1L3MBTL1LMNAPOLB
SCHEMBL25226863 0.85 ALDH1A1 (0.40) ALDH1A1MAPK1L3MBTL1TSHRKMT2A
SCHEMBL25275744 0.84 ALDH1A1 (0.40) ALDH1A1MAPK1L3MBTL1LMNATSHR
SCHEMBL30453247 0.84 ALDH1A1 (0.55) ALDH1A1MAPK1L3MBTL1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4566608-A2 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION Gilead Sciences, Inc. (US) 2025-06-11 — — EP disclosed
US-20250179102-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2025-06-05 — — US disclosed
EP-4440702-B1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES INC (US) 2025-05-21 — — EP disclosed
EP-4445900-B1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES INC (US) 2025-05-21 — — EP disclosed
US-12187753-B2 Therapeutics compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2025-01-07 — — US disclosed
EP-4445900-A2 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION Gilead Sciences, Inc. (US) 2024-10-16 — — EP disclosed
EP-4440702-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2024-10-09 — — EP disclosed
CN-118369325-A Therapeutic compounds for HIV virus infection 吉利德科学公司 2024-07-19 — — CN disclosed
US-20240132527-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2024-04-25 — — US disclosed
US-11787825-B2 Therapeutic compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2023-10-17 — — US disclosed
US-11787825-B2 Therapeutic compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2023-10-17 — — US disclosed
US-20230203069-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2023-06-29 — — US disclosed
US-20230203069-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2023-06-29 — — US disclosed
WO-2023102239-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2023-06-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179102-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION CD4, HAVCR2, MAVS ALDH1A1 1512/4885MAPK1 4303/4885L3MBTL1 1204/4885
US-11787825-B2 Therapeutic compounds for HIV virus infection HAVCR2, MAVS, CD4 ALDH1A1 1718/4885MAPK1 4199/4885L3MBTL1 1303/4885
US-12187753-B2 Therapeutics compounds for HIV virus infection CD4, HAVCR2, MAVS ALDH1A1 1512/4885MAPK1 4303/4885L3MBTL1 1204/4885
US-20230203069-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION HAVCR2, MAVS, CD4 ALDH1A1 1718/4885MAPK1 4199/4885L3MBTL1 1303/4885
US-20240132527-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION CD4, HAVCR2, MAVS ALDH1A1 1512/4885MAPK1 4303/4885L3MBTL1 1204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback