SCHEMBL25255619

SCHEMBL25255619

CN(CCCC(=O)OCc1ccccc1)C(=O)OCOP(=O)(OC(C)(C)C)OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.37
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ LMNA P02545 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ LTA4H P09960 1/20 0.35
▸ FDFT1 P37268 1/20 0.35
▸ F13A1 P00488 1/20 0.34
▸ TGM2 P21980 1/20 0.34
▸ TGM1 P22735 1/20 0.34
▸ HDAC1 Q13547 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25787610 0.89 F13A1 (0.41) L3MBTL1ALDH1A1MAPK1F13A1TGM2
SCHEMBL30392722 0.88 ALDH1A1 (0.44) L3MBTL1ALDH1A1MAPK1LMNAPOLB
SCHEMBL25275744 0.87 ALDH1A1 (0.40) L3MBTL1ALDH1A1MAPK1LMNAKMT2A
SCHEMBL25690727 0.85 ALDH1A1 (0.46) L3MBTL1ALDH1A1MAPK1LMNAPOLB
SCHEMBL25250198 0.85 CCR6 (0.39) ALOX5L3MBTL1ALDH1A1MAPK1LMNA
SCHEMBL25217965 0.85 CCR6 (0.37) ALOX5L3MBTL1ALDH1A1MAPK1LMNA
SCHEMBL30473565 0.84 L3MBTL1 (0.43) L3MBTL1ALDH1A1LMNA
SCHEMBL25226339 0.84 PRSS1 (0.40) L3MBTL1ALDH1A1MAPK1HDAC1
SCHEMBL30392906 0.83 POLB (0.36) L3MBTL1POLB
SCHEMBL25223781 0.82 CCR6 (0.36) L3MBTL1POLBF13A1TGM2TGM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4566608-A2 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION Gilead Sciences, Inc. (US) 2025-06-11 — — EP disclosed
US-20250179102-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2025-06-05 — — US disclosed
EP-4440702-B1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES INC (US) 2025-05-21 — — EP disclosed
EP-4445900-B1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES INC (US) 2025-05-21 — — EP disclosed
US-12187753-B2 Therapeutics compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2025-01-07 — — US disclosed
EP-4445900-A2 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION Gilead Sciences, Inc. (US) 2024-10-16 — — EP disclosed
EP-4440702-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2024-10-09 — — EP disclosed
US-20240132527-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2024-04-25 — — US disclosed
US-11787825-B2 Therapeutic compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2023-10-17 — — US disclosed
US-11787825-B2 Therapeutic compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2023-10-17 — — US disclosed
US-20230203069-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2023-06-29 — — US disclosed
US-20230203069-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2023-06-29 — — US disclosed
WO-2023102239-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2023-06-08 — — WO disclosed
WO-2023102239-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2023-06-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179102-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION CD4, HAVCR2, MAVS ALOX5 565/4885L3MBTL1 1204/4885ALDH1A1 1512/4885
US-11787825-B2 Therapeutic compounds for HIV virus infection HAVCR2, MAVS, CD4 ALOX5 674/4885L3MBTL1 1303/4885ALDH1A1 1718/4885
US-12187753-B2 Therapeutics compounds for HIV virus infection CD4, HAVCR2, MAVS ALOX5 565/4885L3MBTL1 1204/4885ALDH1A1 1512/4885
US-20230203069-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION HAVCR2, MAVS, CD4 ALOX5 674/4885L3MBTL1 1303/4885ALDH1A1 1718/4885
US-20240132527-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION CD4, HAVCR2, MAVS ALOX5 565/4885L3MBTL1 1204/4885ALDH1A1 1512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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