SCHEMBL2569189

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2566158	0.90	NPC1 (0.49)	FKBP1ANPC1RAB9AALDH1A1SIGMAR1
	SCHEMBL2569043	0.85	NPC1 (0.50)	FKBP1ANPC1RAB9AALDH1A1SIGMAR1
	SCHEMBL5122022	0.85	RAB9A (0.50)	FKBP1ANPC1RAB9AALDH1A1PKM
	SCHEMBL2566934	0.83	ALDH1A1 (0.54)	FKBP1ANPC1RAB9AALDH1A1PKM
	SCHEMBL493175	0.81	RAB9A (0.58)	FKBP1ANPC1RAB9AALDH1A1MMP1
	SCHEMBL22633436	0.81	NPC1 (0.62)	FKBP1ANPC1RAB9AMMP1MMP3
	SCHEMBL2567510	0.80	BDKRB1 (0.46)	FKBP1ACHRM3SIGMAR1POLB
	SCHEMBL3777024	0.79	BDKRB1 (0.46)	CHRM3SIGMAR1POLB
	SCHEMBL5128989	0.78	RAB9A (0.46)	FKBP1ANPC1RAB9AALDH1A1PKM
	SCHEMBL2566355	0.77	NPC1 (0.49)	NPC1RAB9AALDH1A1SIGMAR1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.