Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 2/20 | 0.61 |
| ▸ | FEN1 | P39748 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30567820 | 0.98 | ERCC5 (0.59) | ERCC5FEN1TSHRTAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL9854847 | 0.98 | ERCC5 (0.59) | ERCC5FEN1TSHRTAS1R3TAS1R1 | |
| SCHEMBL1318546 | 0.83 | ERCC5 (0.58) | ERCC5FEN1CES2CES1ALDH1A1 | |
| SCHEMBL30839506 | 0.83 | ERCC5 (0.58) | ERCC5FEN1CES2CES1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL23780883 | 0.82 | ERCC5 (0.56) | ERCC5FEN1CES2CES1ALDH1A1 | |
| SCHEMBL3142115 | 0.82 | ERCC5 (0.62) | ERCC5FEN1TSHRTAS1R3TAS1R1 | |
| SCHEMBL30547190 | 0.80 | ERCC5 (0.61) | ERCC5FEN1TSHRTAS1R3TAS1R1 | |
| SCHEMBL15189611 | 0.80 | ERCC5 (0.61) | ERCC5FEN1TSHRTAS1R3TAS1R1 | |
| SCHEMBL2255346 | 0.80 | ERCC5 (0.61) | ERCC5FEN1TSHRTAS1R3TAS1R1 | |
| SCHEMBL1199039 | 0.80 | ERCC5 (0.61) | ERCC5FEN1TSHRTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174910-B1 | PROCESS FOR THE PREPARATION OF 4-PHENYL-PYRROLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1990-04-04 | — | — | EP | claimed |
| US-4812580-A | FROM A PHENACYLAMINE AND ACRYLONITRILE DERIVATIVE, CYCLIZATION, FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1989-03-14 | — | — | US | claimed |
| EP-0174910-A2 | Process for the preparation of 4-phenyl-pyrrole derivatives | CIBA-GEIGY AG (CH) | 1986-03-19 | — | — | EP | claimed |
| US-9180120-B2 | Substituted N-phenethyltriazoloneacetamides and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-10 | — | — | US | disclosed |
| US-9180120-B2 | Substituted N-phenethyltriazoloneacetamides and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-10 | — | — | US | disclosed |
| EP-2619188-B1 | SUBSTITUTED N-PHENETHYLTRIAZOLONEACETAMIDES AND USE THEREOF | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | disclosed |
| US-20130225646-A1 | SUBSTITUTED N-PHENETHYLTRIAZOLONEACETAMIDES AND USE THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-29 | — | — | US | disclosed |
| US-20130225646-A1 | SUBSTITUTED N-PHENETHYLTRIAZOLONEACETAMIDES AND USE THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-29 | — | — | US | disclosed |
| WO-2012028644-A1 | SUBSTITUTED N-PHENETHYLTRIAZOLONEACETAMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-08 | — | — | WO | disclosed |
| US-4981990-A | FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1991-01-01 | — | — | US | disclosed |
| EP-0174910-B1 | PROCESS FOR THE PREPARATION OF 4-PHENYL-PYRROLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1990-04-04 | — | — | EP | disclosed |
| US-4812580-A | FROM A PHENACYLAMINE AND ACRYLONITRILE DERIVATIVE, CYCLIZATION, FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1989-03-14 | — | — | US | disclosed |
| US-4709053-A | FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1987-11-24 | — | — | US | disclosed |
| EP-0174910-A2 | Process for the preparation of 4-phenyl-pyrrole derivatives | CIBA-GEIGY AG (CH) | 1986-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225646-A1 | SUBSTITUTED N-PHENETHYLTRIAZOLONEACETAMIDES AND USE THEREOF | TNNT2, TNNI3, PNMT | ERCC5 3953/4885FEN1 2627/4885TSHR 3359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.