SCHEMBL2569723

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2564657	0.85	CACNA2D1 (0.42)	TRPV4GRM5POLBTHRB
	SCHEMBL3772158	0.85	CACNA2D1 (0.42)	TRPV4GRM5POLBTHRB
	SCHEMBL3775346	0.85	GRM5 (0.37)	TRPV4GRM5POLBTHRBMAPT
	SCHEMBL2568226	0.85	GRM5 (0.37)	TRPV4GRM5POLBTHRBMAPT
	SCHEMBL5128421	0.85	EPHX2 (0.44)	TRPV4GRM5POLB
	SCHEMBL2564439	0.84	LMNA (0.41)	LMNAPOLBSMN1; SMN2USP2ALDH1A1
	SCHEMBL2571091	0.83	PSEN1 (0.43)	GRM5
	SCHEMBL2570113	0.83	PSEN1 (0.44)	—
	SCHEMBL5131980	0.83	EPHX2 (0.43)	TRPV4GRM5POLBSMN1; SMN2ALDH1A1
	SCHEMBL3813955	0.82	POLB (0.43)	TRPV4POLBSMN1; SMN2PTGDR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.