SCHEMBL3772158

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2564657	1.00	CACNA2D1 (0.42)	CACNA2D1CACNA1BCACNB1CACNA1CBDKRB1
	SCHEMBL2566754	0.90	GRM5 (0.40)	BDKRB1GRM5GAAPSEN1PSEN2
	SCHEMBL3769761	0.90	GRM5 (0.40)	BDKRB1GRM5GAAPSEN1PSEN2
	SCHEMBL2568399	0.87	ACHE (0.43)	BDKRB1GRM5HTR6GAAPSEN1
	SCHEMBL2568226	0.86	GRM5 (0.37)	GRM5THRBHTR6GAATRPV4
	SCHEMBL3775346	0.86	GRM5 (0.37)	GRM5THRBHTR6GAATRPV4
	SCHEMBL2569723	0.85	TRPV4 (0.48)	GRM5THRBTRPV4POLB
	SCHEMBL2571091	0.83	PSEN1 (0.43)	GRM5PSEN1PSEN2APH1BNCSTN
	SCHEMBL2570113	0.83	PSEN1 (0.44)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL15204015	0.82	BDKRB1 (0.48)	CACNA2D1CACNA1BCACNB1CACNA1CBDKRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.