SCHEMBL2569844

SCHEMBL2569844

CCN(CC)c1ccc(C(=O)CN2C=CSC2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42
HDAC5 Q9UQL6 1/20 0.42
HSD11B1 P28845 1/20 0.42
MAPT P10636 9/20 0.40
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
POLB P06746 3/20 0.40
NOX1 Q9Y5S8 2/20 0.40
GAA P10253 2/20 0.40
MCL1 Q07820 1/20 0.40
ALDH1A1 P00352 6/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3847435 0.99 HDAC3 (0.41) HDAC3HDAC4HDAC1HDAC7HDAC2
Bromide SCHEMBL3847332 0.99 HDAC3 (0.41) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL7074124 0.79 NPC1 (0.43) KMT2AMEN1POLBGAAALDH1A1
SCHEMBL6936037 0.79 GSK3B (0.44) MAPTKMT2AMEN1GAAALDH1A1
SCHEMBL6935144 0.79 GSK3B (0.44) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL8390047 0.78 ALDH1A1 (0.52) HDAC3HDAC4HDAC1HDAC7HDAC2
Bromide SCHEMBL3847336 0.77 NPC1 (0.42) KMT2AMEN1POLBGAAALDH1A1
Bromide SCHEMBL2947798 0.77 RAB9A (0.46) HDAC3HDAC4HDAC1HDAC7HDAC2
Bromide SCHEMBL4114709 0.77 RAB9A (0.46) MAPTKMT2AMEN1GAAALDH1A1
Bromide SCHEMBL122634 0.77 ALDH1A1 (0.43) MAPTKMT2AMEN1GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7144570-B2 Sunscreen compositions and methods of use thereof ALTEON, INC. (US) 2006-12-05 US claimed
US-7078022-B2 Sunscreen compositions and methods of use thereof AVON PRODUCTS, INC. (US) 2006-07-18 US claimed
US-20050063924-A1 Sunscreen compositions and methods of use thereof SYNVISTA THERAPEUTICS, INC. 2005-03-24 US claimed
US-20040120905-A1 Sunscreen compositions and methods of use thereof SYNVISTA THERAPEUTICS, INC. 2004-06-24 US claimed
WO-2003099249-A1 SUNSCREEN COMPOSITIONS AND CONTAINING AZOLIUM COMPOUNDS ALTEON, INC. (US) 2003-12-04 WO claimed
WO-2003099241-A2 SUNSCREEN COMPOSITIONS AND METHODS OF USE THEREOF MANISCALCO TONY (US) 2003-12-04 WO claimed
EP-0808163-B1 USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS ALTEON INC (US) 2003-07-23 EP claimed
US-6007865-A FOR INHIBITING AND REVERSING NONENZYMATIC CROSS-LINKING (PROTEIN AGING), TREATING KIDNEY DAMAGE AND TREATING COMPLICATIONS OF DIABETES, PREVENTING FOOD SPOILAGE ALTEON INC. 1999-12-28 US claimed
EP-2384193-B1 VITAMIN D PROMOTING SUNSCREEN ARMSTRONG ERNEST T (US) 2025-08-06 EP disclosed
US-9724544-B2 Vitamin D promoting sunscreen Armstrong, Ernest T. (US) 2017-08-08 US disclosed
EP-2384193-A2 VITAMIN D PROMOTING SUNSCREEN Armstrong, Ernest T. (US) 2011-11-09 EP disclosed
US-20110268678-A1 VITAMIN D FORMING SUNSCREEN ARMSTRONG ERNEST T 2011-11-03 US disclosed
WO-2010076731-A2 VITAMIN D PROMOTING SUNSCREEN ARMSTRONG ERNEST T (US) 2010-07-08 WO disclosed
US-7144570-B2 Sunscreen compositions and methods of use thereof ALTEON, INC. (US) 2006-12-05 US disclosed
US-20050063924-A1 Sunscreen compositions and methods of use thereof SYNVISTA THERAPEUTICS, INC. 2005-03-24 US disclosed
US-20040120905-A1 Sunscreen compositions and methods of use thereof SYNVISTA THERAPEUTICS, INC. 2004-06-24 US disclosed
WO-2003099241-A3 SUNSCREEN COMPOSITIONS AND METHODS OF USE THEREOF MANISCALCO TONY (US) 2004-04-01 WO disclosed
WO-2003099249-A1 SUNSCREEN COMPOSITIONS AND CONTAINING AZOLIUM COMPOUNDS ALTEON, INC. (US) 2003-12-04 WO disclosed
WO-2003099241-A2 SUNSCREEN COMPOSITIONS AND METHODS OF USE THEREOF MANISCALCO TONY (US) 2003-12-04 WO disclosed
WO-2003099241-A2 SUNSCREEN COMPOSITIONS AND METHODS OF USE THEREOF MANISCALCO TONY (US) 2003-12-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040120905-A1 Sunscreen compositions and methods of use thereof TYR, TRPA1, SUN2 HDAC3 1063/4885HDAC4 611/4885HDAC1 1117/4885
US-20050063924-A1 Sunscreen compositions and methods of use thereof SUN2, CUTA, TYR HDAC3 1571/4885HDAC4 810/4885HDAC1 1006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.