SCHEMBL2569883

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2569886	1.00	BACE1 (0.38)	BACE1BRD4MAPTTP53AURKB
	SCHEMBL2570400	0.95	CHEK1 (0.38)	BACE1BRD4MAPTTP53AURKB
	SCHEMBL2570403	0.95	CHEK1 (0.38)	BACE1BRD4MAPTTP53AURKB
	SCHEMBL2570164	0.94	NAMPT (0.39)	BACE1MAPTTP53AURKBCHEK1
	SCHEMBL26929196	0.91	BACE1 (0.37)	BACE1MAPTTP53AURKBKDR
	SCHEMBL2570418	0.89	CHEK1 (0.40)	BACE1TP53AURKBCHEK1DAPK3
	SCHEMBL2570168	0.89	HPGD (0.38)	BACE1BRD4MAPTTP53PDK1
	SCHEMBL2571801	0.88	SENP1 (0.38)	BACE1MAPTTP53AURKBCHEK1
	SCHEMBL30737799	0.88	SENP1 (0.38)	BACE1MAPTTP53AURKBCHEK1
	SCHEMBL2571796	0.88	SENP1 (0.38)	BACE1MAPTTP53AURKBCHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.