SCHEMBL2570168

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2570421	0.95	HPGD (0.37)	HPGDBACE1PDK2TP53MCHR1
	SCHEMBL26929196	0.91	BACE1 (0.37)	HPGDBACE1PDK2TP53MAPT
	SCHEMBL2569886	0.89	BACE1 (0.38)	HPGDBACE1PDK2TP53PDK1
	SCHEMBL2569883	0.89	BACE1 (0.38)	HPGDBACE1PDK2TP53PDK1
	SCHEMBL2571796	0.88	SENP1 (0.38)	HPGDBACE1TP53MAPTALDH1A1
	SCHEMBL30737799	0.88	SENP1 (0.38)	HPGDBACE1TP53MAPTALDH1A1
	SCHEMBL2571801	0.88	SENP1 (0.38)	HPGDBACE1TP53MAPTALDH1A1
	SCHEMBL2566898	0.88	TP53 (0.42)	HPGDBACE1PDK2TP53MCHR1
	SCHEMBL2571806	0.88	ALDH1A1 (0.35)	HPGDBACE1PDK2TP53PDK1
	SCHEMBL2567836	0.88	RXFP1 (0.43)	TP53NAMPTMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.