SCHEMBL25699129

SCHEMBL25699129

Brc1ccc2c(c1)[Si](c1ccccc1)(c1ccccc1)c1ccccc1O2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.52
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
SIRT1 Q96EB6 1/20 0.32
HTR2A P28223 4/20 0.31
HTR2C P28335 4/20 0.31
DRD2 P14416 2/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2C P18825 1/20 0.31
DRD1 P21728 1/20 0.31
HTR7 P34969 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31
CYP19A1 P11511 1/20 0.31
CYP2A6 P11509 1/20 0.31
EGFR P00533 1/20 0.30
NPC1 O15118 1/20 0.30
MAPT P10636 1/20 0.30
ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15714027 0.95 AHR (0.52) AHRCA12CA2CA9SIRT1
SCHEMBL20150634 0.88 AHR (0.42) AHR
SCHEMBL15714208 0.86 AHR (0.43) AHRCA12CA2CA9
SCHEMBL20544653 0.84 MAOA (0.36) AHR
SCHEMBL21666728 0.82 AHR (0.31) AHR
SCHEMBL20150635 0.75 CYP1A2 (0.36) AHRNPC1MAPTRAB9ASMN1; SMN2
SCHEMBL11978737 0.74 PTPRC (0.39) AHRCA2CA9CYP19A1CYP2A6
SCHEMBL24643751 0.74 KDM4E (0.33) MAPT
SCHEMBL15713247 0.74 PLA2G2A (0.37) AHRCA12CA9NPC1MAPT
SCHEMBL26494923 0.74 SMN1; SMN2 (0.36) AHRNPC1MAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192729-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230192729-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192729-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE LAGE3, EMC1, CYP2E1 AHR 458/4885CA12 1410/4885CA2 3802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.