Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25246994 | 0.82 | PGR (0.35) | PGR | |
| SCHEMBL25699160 | 0.78 | PGR (0.36) | ALDH1A1PGRPKMKDM4ECA1 | |
| SCHEMBL9864782 | 0.67 | PSIP1 (0.31) | — | |
| SCHEMBL25420324 | 0.67 | CTSL (0.37) | — | |
| SCHEMBL16492321 | 0.66 | ALDH1A1 (0.65) | ALDH1A1CYP2C9SMN1; SMN2KMT2AVCAM1 | |
| SCHEMBL12763788 | 0.65 | KDM4E (0.34) | ALDH1A1SMN1; SMN2PGRMEN1KMT2A | |
| SCHEMBL4613568 | 0.65 | CYP19A1 (0.67) | ALDH1A1CYP2C9CYP19A1 | |
| SCHEMBL4615617 | 0.64 | PGR (0.50) | ALDH1A1SMN1; SMN2PGRKMT2ACYP19A1 | |
| SCHEMBL13620942 | 0.63 | — | — | |
| SCHEMBL5007597 | 0.62 | ALDH1A1 (0.41) | ALDH1A1CYP2C9SMN1; SMN2PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094830-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |