Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20715548 | 0.79 | SLC6A2 (0.53) | SLC6A2SLC6A3SLC6A4MAOAIDO1 | |
| SCHEMBL19140754 | 0.78 | SLC6A4 (0.44) | SLC6A2SLC6A3SLC6A4MAOATAAR1 | |
| SCHEMBL25583216 | 0.78 | TRPA1 (0.52) | SLC6A2SLC6A3SLC6A4MAOAIDO1 | |
| SCHEMBL21504837 | 0.78 | MAPK1 (0.41) | SLC6A2SLC6A3MEN1CYP1A2RAB9A | |
| SCHEMBL13242159 | 0.77 | SIGMAR1 (0.54) | SLC6A2SLC6A3SLC6A4MAOAMEN1 | |
| SCHEMBL12327240 | 0.77 | SIGMAR1 (0.54) | SLC6A2SLC6A3SLC6A4MAOAMEN1 | |
| SCHEMBL764989 | 0.77 | SLC6A2 (0.67) | SLC6A2SLC6A3SLC6A4IDO1CYP2C9 | |
| SCHEMBL2326795 | 0.75 | SLC6A2 (0.64) | SLC6A2SLC6A3SLC6A4IDO1ACACB | |
| SCHEMBL23511482 | 0.74 | CYP3A4 (0.43) | SLC6A2SLC6A3SLC6A4MAOAMEN1 | |
| SCHEMBL11133775 | 0.74 | SLC6A2 (0.52) | SLC6A2SLC6A3SLC6A4IDO1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086801-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |