Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20821152 | 0.81 | CYP3A4 (0.41) | CYP3A4CYP2C19CYP1A2CYP2C9ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL29040632 | 0.79 | CYP3A4 (0.47) | CYP3A4CYP2C19CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL12327240 | 0.77 | SIGMAR1 (0.54) | CYP2D6SLC6A2SLC6A4SLC6A3MAOA | |
| SCHEMBL13242159 | 0.77 | SIGMAR1 (0.54) | CYP2D6SLC6A2SLC6A4SLC6A3MAOA | |
| SCHEMBL104529 | 0.77 | CYP3A4 (0.48) | CYP3A4CYP2C19CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL26329006 | 0.75 | CYP3A4 (0.47) | CYP3A4CYP2C19CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL21851278 | 0.75 | CYP3A4 (0.47) | CYP3A4CYP2C19CYP1A2CYP2C9ALDH1A1 | |
| Iodide SCHEMBL1750931 | 0.75 | CYP2C9 (0.47) | CYP3A4CYP2C19CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL19140754 | 0.74 | SLC6A4 (0.44) | CYP3A4ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25583216 | 0.74 | TRPA1 (0.52) | SLC6A2SLC6A4SLC6A3LOXL2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210179612-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION | 2021-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210179612-A1 | MASP-2 INHIBITORS AND METHODS OF USE | MASP2, METAP2, SPINT2 | CYP3A4 4706/4885CYP2C19 4866/4885CYP1A2 4271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.