Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13242159 | 1.00 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6011566 | 0.83 | SIGMAR1 (0.56) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27865935 | 0.83 | SIGMAR1 (0.56) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8542522 | 0.79 | SIGMAR1 (0.52) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20441016 | 0.79 | SIGMAR1 (0.52) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10012176 | 0.79 | SIGMAR1 (0.52) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3099528 | 0.78 | TAAR1 (0.50) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23511482 | 0.77 | CYP3A4 (0.43) | SLC6A2SLC6A4SLC6A3MAOACYP2D6 | |
| SCHEMBL21186437 | 0.77 | TSHR (0.46) | OPRK1MEN1KMT2A | |
| SCHEMBL19140754 | 0.77 | SLC6A4 (0.44) | TAAR1SLC6A2SLC6A4SLC6A3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2022-05-10 | — | — | US | disclosed |
| US-20210237394-A1 | Acoustic material structure and method for assembling same and acoustic radiation structure | Component Technologies, L.L.C. (US) | 2021-08-05 | — | — | US | disclosed |
| US-10604506-B2 | Modulators of estrogen receptor proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2020-03-31 | — | — | US | disclosed |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | disclosed |
| US-8017552-B2 | Has thermal transfer layer on a support, can stably keep up good capability of peeling off an image-receiving sheet without being affected by properties of a support, running stability | FUJIFILM CORPORATION (JP) | 2011-09-13 | — | — | US | disclosed |
| US-20080248949-A1 | HEAT-SENSITIVE TRANSFER SHEET AND IMAGE-FORMATION METHOD | FUJIFILM CORPORATION (JP) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10604506-B2 | Modulators of estrogen receptor proteolysis and associated methods of use | ADRM1, MDM2, ESR2 | SIGMAR1 2267/4885TAAR1 3669/4885SLC6A2 4551/4885 |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | HDGF, F11, F12 | SIGMAR1 1212/4885TAAR1 3874/4885SLC6A2 4635/4885 |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | HDGF, F11, F12 | SIGMAR1 1212/4885TAAR1 3874/4885SLC6A2 4635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.