Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GNRHR | P30968 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27950175 | 0.76 | CA9 (0.71) | KMT2ACA1CA2CA9CYP19A1 | |
| SCHEMBL13972679 | 0.74 | CA1 (0.68) | KMT2ACA1CA2CA9PKM | |
| SCHEMBL20946426 | 0.73 | CA1 (0.77) | KMT2ACA1CA2CA9PKM | |
| SCHEMBL7507787 | 0.73 | CA1 (0.71) | KMT2ACA1CA2CA9PKM | |
| SCHEMBL13959180 | 0.72 | CA1 (0.66) | CA1CA2CA9PKMCYP19A1 | |
| SCHEMBL1893565 | 0.72 | ALDH1A1 (0.76) | CA1CA2CA9PKMCYP19A1 | |
| SCHEMBL6289448 | 0.72 | CYP19A1 (0.78) | KMT2ACA1CA2CA9CYP19A1 | |
| SCHEMBL4663044 | 0.72 | KEAP1 (0.76) | KMT2ACA1CA2CA9PKM | |
| SCHEMBL25700619 | 0.72 | CNR2 (0.51) | KMT2APOLBALDH1A1LMNARECQL | |
| SCHEMBL17979485 | 0.71 | THRB (0.50) | KMT2ACA1CA2CA9CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094830-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |