Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 4/20 | 0.48 |
| ▸ | FGB | P02675 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GNRHR | P30968 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17979460 | 0.89 | ALDH1A1 (0.61) | THRBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL17979432 | 0.86 | THRB (0.43) | THRBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL19865855 | 0.82 | MAPT (0.44) | THRBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL17979542 | 0.78 | MAPT (0.41) | THRBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL17979543 | 0.78 | MAPT (0.41) | THRBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL17979340 | 0.72 | BRPF1 (0.37) | ALDH1A1MAPTKMT2ALMNAPOLB | |
| SCHEMBL17979482 | 0.72 | BRPF1 (0.41) | ALDH1A1MEN1MAPTKMT2ACA1 | |
| SCHEMBL19865934 | 0.72 | MAPT (0.43) | THRBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL25700617 | 0.71 | KMT2A (0.57) | THRBALDH1A1KMT2ACYP19A1RECQL | |
| SCHEMBL21043867 | 0.70 | POLB (0.59) | THRBMAPTCYP19A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |
| EP-3256447-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | Syngenta Participations AG (CH) | 2017-12-20 | — | — | EP | disclosed |
| WO-2016128317-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-18 | — | — | WO | disclosed |