Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257065 | 0.88 | TDP1 (0.60) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL16638505 | 0.86 | ALDH1A1 (0.55) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL257067 | 0.83 | SMN1; SMN2 (0.64) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL16099017 | 0.76 | WNT3A (0.69) | ALOX15SMN1; SMN2 | |
| SCHEMBL9921691 | 0.76 | ATM (0.76) | ALDH1A1HPGDALOX15ATMKDM4E | |
| SCHEMBL10777343 | 0.75 | TDP1 (0.55) | MEN1KMT2APOLBGAASMN1; SMN2 | |
| SCHEMBL792326 | 0.75 | L3MBTL1 (0.61) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL13803995 | 0.74 | ALDH1A1 (0.62) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL9967741 | 0.74 | TDP1 (0.58) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL13597049 | 0.74 | ALDH1A1 (0.77) | MEN1KMT2APOLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028578-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |