Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | CFD | P00746 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ACLY | P53396 | 10/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GGT1 | P19440 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13205894 | 0.93 | CFD (0.61) | CFDACLYKDM4EHDAC8ALDH1A1 | |
| SCHEMBL1317055 | 0.91 | POLB (0.56) | POLBCFDLMNANPSR1ACLY | |
| SCHEMBL13206302 | 0.89 | ACLY (0.53) | POLBCFDLMNANPSR1ACLY | |
| SCHEMBL12369705 | 0.88 | KDM4E (0.56) | CFDLMNAACLYKDM4EALDH1A1 | |
| SCHEMBL13205881 | 0.88 | CFD (0.51) | POLBCFDLMNANPSR1ACLY | |
| SCHEMBL1316660 | 0.87 | POLB (0.50) | POLBCFDLMNANPSR1ACLY | |
| SCHEMBL2571108 | 0.84 | LRRK2 (0.59) | POLBLMNANPSR1ACLYKDM4E | |
| SCHEMBL1316555 | 0.82 | ACLY (0.56) | ACLYKDM4ETRPM2HDAC2 | |
| SCHEMBL13206267 | 0.82 | ACLY (0.60) | NPSR1ACLY | |
| SCHEMBL2575383 | 0.81 | ACLY (0.45) | POLBCFDLMNANPSR1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385036-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | Toyama Chemical Co., Ltd. (JP) | 2011-11-09 | — | — | EP | disclosed |