SCHEMBL2575383

SCHEMBL2575383

CC(=O)Oc1ccc(B2OC(C)(C)C(C)(C)O2)cc1C(=O)Nc1cc(-c2ccccc2)ccc1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACLY P53396 9/20 0.45
CFD P00746 1/20 0.44
LIPG Q9Y5X9 3/20 0.43
LPL P06858 2/20 0.43
POLB P06746 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PRSS12 P56730 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
ESR1 P03372 1/20 0.38
ITGB3 P05106 1/20 0.38
ITGA2B P08514 1/20 0.38
HMGB1 P09429 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
GGT1 P19440 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1316797 0.89 LIPG (0.38) ACLYCFDLIPGLPLPOLB
SCHEMBL13205894 0.85 CFD (0.61) ACLYCFDPRSS12KDM4EALDH1A1
SCHEMBL13206302 0.81 ACLY (0.53) ACLYCFDPOLBMEN1KMT2A
SCHEMBL2570784 0.81 POLB (0.56) ACLYCFDPOLBKDM4EALDH1A1
SCHEMBL12369705 0.80 KDM4E (0.56) ACLYCFDKMT2APRSS12KDM4E
SCHEMBL13205881 0.80 CFD (0.51) ACLYCFDPOLBMEN1KMT2A
SCHEMBL12117768 0.76 LIPG (0.41) ACLYLIPGLPLKEAP1NFE2L2
SCHEMBL13206267 0.74 ACLY (0.60) ACLYMEN1KMT2APRSS12NPSR1
SCHEMBL12165985 0.73 CFD (0.50) ACLYCFDPOLBMEN1KMT2A
SCHEMBL1317055 0.73 POLB (0.56) ACLYCFDPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 US disclosed
EP-2385036-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2011-11-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 ACLY 295/4885CFD 2776/4885LIPG 2586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.