Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 4/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311268 | 0.93 | DRD2 (0.52) | DRD2ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL2306719 | 0.82 | ALDH1A1 (0.62) | DRD2ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL4594096 | 0.82 | AKR1C3 (0.46) | DRD2ALDH1A1LMNAMAPTPNMT | |
| SCHEMBL30130812 | 0.79 | NR1H2 (0.67) | DRD2ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL396485 | 0.79 | NR1H2 (0.67) | DRD2ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL6499027 | 0.79 | ESR2 (0.69) | DRD2ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL2062288 | 0.77 | PNMT (0.49) | DRD2ALDH1A1LMNAMAPTPNMT | |
| SCHEMBL7738183 | 0.76 | DRD2 (0.45) | DRD2ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL7299890 | 0.76 | SLC18A3 (0.48) | ALDH1A1LMNAMAPTADRA2AMAPK1 | |
| SCHEMBL6097088 | 0.76 | MEN1 (0.53) | DRD2ALDH1A1LMNAMAPTPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B9 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | disclosed |