Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570871 | 0.82 | DRD2 (0.49) | AKR1C3ADRA2APNMTGRIN2BALDH1A1 | |
| SCHEMBL2062288 | 0.81 | PNMT (0.49) | AKR1C3ADRA2APNMTGRIN2BALDH1A1 | |
| SCHEMBL17797648 | 0.81 | HPGD (0.51) | AKR1C3ADRA2APNMTGRIN2BHPGD | |
| SCHEMBL6097088 | 0.79 | MEN1 (0.53) | ADRA2APNMTHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL3467138 | 0.77 | DRD2 (0.48) | AKR1C3ADRA2APNMTGRIN2BDRD2 | |
| SCHEMBL1950525 | 0.77 | PNMT (0.54) | ADRA2APNMTGRIN2BHPGDALDH1A1 | |
| SCHEMBL7738183 | 0.77 | DRD2 (0.45) | AKR1C3ADRA2APNMTGRIN2BHPGD | |
| SCHEMBL2310023 | 0.77 | ALDH1A1 (0.55) | AKR1C3ADRA2APNMTHPGDALDH1A1 | |
| SCHEMBL30709850 | 0.76 | PNMT (0.65) | ADRA2APNMTGRIN2BALDH1A1MEN1 | |
| SCHEMBL9483063 | 0.76 | PNMT (0.65) | ADRA2APNMTGRIN2BALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-A1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | Boehringer Ingelheim International GmbH (DE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007003536-A1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-01-11 | — | — | WO | disclosed |