Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 14/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12111813 | 0.81 | THRB (0.49) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL25719241 | 0.79 | CA2 (0.34) | P2RY2P2RY4CYP2D6THRBHSD17B10 | |
| SCHEMBL23829163 | 0.79 | CA2 (0.43) | P2RY2P2RY4CYP2D6THRBHSD17B10 | |
| SCHEMBL25712758 | 0.77 | POLA1 (0.39) | P2RY2P2RY4 | |
| SCHEMBL25712626 | 0.74 | P2RY2 (0.42) | P2RY2P2RY4 | |
| SCHEMBL18512680 | 0.74 | POLB (0.55) | P2RY2P2RY4 | |
| SCHEMBL6973818 | 0.73 | CYP2D6 (0.42) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL26074117 | 0.73 | FBP1 (0.53) | P2RY2P2RY4 | |
| SCHEMBL14985142 | 0.73 | FBP1 (0.53) | P2RY2P2RY4 | |
| SCHEMBL13259502 | 0.73 | FBP1 (0.53) | P2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131914-B1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2023-05-10 | — | — | EP | disclosed |