SCHEMBL2571382

SCHEMBL2571382

c1ccc(COC2CCO2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
CTSL P07711 2/20 0.42
CTSB P07858 2/20 0.42
CTSK P43235 2/20 0.42
OPRM1 P35372 2/20 0.41
OPRL1 P41146 2/20 0.41
DPP4 P27487 1/20 0.41
CTSV O60911 1/20 0.41
CTSS P25774 1/20 0.41
CTSC P53634 1/20 0.41
CTSF Q9UBX1 1/20 0.41
TACR1 P25103 2/20 0.40
IDO1 P14902 1/20 0.40
PSEN1 P49768 2/20 0.40
PSEN2 P49810 2/20 0.40
APH1B Q8WW43 2/20 0.40
NCSTN Q92542 2/20 0.40
APH1A Q96BI3 2/20 0.40
PSENEN Q9NZ42 2/20 0.40
SIGMAR1 Q99720 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7445879 0.91 TACR1 (0.47) TSHRCTSLCTSBCTSKDPP4
SCHEMBL4184332 0.89 KDM4C (0.47) CTSLCTSBCTSKTACR1PSEN1
SCHEMBL11258174 0.88 KDM4C (0.46) CTSLCTSBCTSKTACR1
SCHEMBL21697528 0.86 CTSL (0.43) CTSLCTSBCTSKOPRM1OPRL1
SCHEMBL246409 0.85 DPP4 (0.38) CTSLCTSBCTSKOPRM1OPRL1
SCHEMBL6099668 0.83 TSHR (0.46) TSHRCTSLCTSBCTSKOPRM1
SCHEMBL2510432 0.82 MEN1 (0.39) TSHRCTSLCTSBCTSKOPRM1
SCHEMBL14527725 0.82 TSHR (0.44) TSHRCTSLCTSBCTSKOPRM1
SCHEMBL9171466 0.82 TSHR (0.44) TSHRCTSLCTSBCTSKOPRM1
SCHEMBL13822689 0.80 CTSL (0.38) CTSLCTSBCTSKOPRM1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283548-B1 METHOD FOR PREPARING POLYOLS ECONIC TECH LTD (GB) 2023-09-20 EP disclosed
US-20220185956-A1 METHOD FOR QUENCHING A POLYMERISATION PROCESS ECONIC TECHNOLOGIES LTD (GB) 2022-06-16 US disclosed
US-20200369829-A1 METHOD FOR PREPARING POLYOLS ECONIC TECHNOLOGIES LTD. (GB) 2020-11-26 US disclosed
US-20200339749-A1 METHODS FOR FORMING POLYCARBONATE ETHER POLYOLS AND HIGH MOLECULAR WEIGHT POLYETHER CARBONATES ECONIC TECHNOLOGIES LTD (GB) 2020-10-29 US disclosed
US-20200339732-A1 RIGID FOAMS ECONIC TECHNOLOGIES LTD (GB) 2020-10-29 US disclosed
US-10774180-B2 Catalysts ECONIC TECHNOLOGIES LTD. (GB) 2020-09-15 US disclosed
US-20200140610-A1 CATALYSTS ECONIC TECHNOLOGIES LTD (GB) 2020-05-07 US disclosed
US-20200062899-A1 METHOD FOR PREPARING POLYCARBONATE ETHER POLYOLS ECONIC TECH LTD (GB) 2020-02-27 US disclosed
US-20190055352-A1 CATALYSTS ECONIC TECHNOLOGIES LTD. (GB) 2019-02-21 US disclosed
US-10030102-B2 Catalysts ECONIC TECHNOLOGIES LTD. (GB) 2018-07-24 US disclosed
WO-2017037441-A9 METHOD FOR PREPARING POLYOLS ECONIC TECHNOLOGIES LIMITED (GB) 2018-02-08 WO disclosed
US-20170204221-A1 Catalysts ECONIC TECHNOLOGIES LTD (GB) 2017-07-20 US disclosed
WO-2017037441-A1 METHOD FOR PREPARING POLYOLS ECONIC TECHNOLOGIES LIMITED (GB) 2017-03-09 WO disclosed
EP-1466946-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2011-11-09 EP disclosed
CN-1314765-C Flame-retardant resin composition POLYPLASTICS CO (JP) 2007-05-09 CN disclosed
US-7205346-B2 halogen-free, fireproof mixture of thermoplastic resins, containing phosphorus compounds, aromatic resins, nitrogen compounds, metal compounds, stabilizer agents and water repellants POLYPLASTICS CO., LTD. (JP) 2007-04-17 US disclosed
CN-1599776-A Flame-retardant resin composition POLYPLASTICS CO (JP) 2005-03-23 CN disclosed
US-20040254270-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-16 US disclosed
EP-1466946-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2004-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200339749-A1 METHODS FOR FORMING POLYCARBONATE ETHER POLYOLS AND HIGH MOLECULAR WEIGHT POLYETHER CARBONATES MCCC2, MT-CO2, SCO2 TSHR 4152/4885CTSL 3157/4885CTSB 3068/4885
US-10774180-B2 Catalysts CA1, CA12, CA4 TSHR 4337/4885CTSL 795/4885CTSB 885/4885
US-20190055352-A1 CATALYSTS CA1, CA12, CA4 TSHR 4337/4885CTSL 795/4885CTSB 885/4885
US-20200140610-A1 CATALYSTS MLX, CA12, CA1 TSHR 1212/4885CTSL 2477/4885CTSB 1985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.