SCHEMBL6099668

SCHEMBL6099668

c1ccc(COC2CO2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
CTSL P07711 2/20 0.44
CTSB P07858 2/20 0.44
CTSK P43235 2/20 0.44
BCHE P06276 1/20 0.43
IDO1 P14902 1/20 0.43
PDPK1 O15530 1/20 0.42
MTOR P42345 1/20 0.42
AGXT P21549 1/20 0.41
CYP2C19 P33261 2/20 0.41
PSEN1 P49768 1/20 0.41
PSEN2 P49810 1/20 0.41
APH1B Q8WW43 1/20 0.41
NCSTN Q92542 1/20 0.41
APH1A Q96BI3 1/20 0.41
PSENEN Q9NZ42 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
SIGMAR1 Q99720 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14527725 0.98 TSHR (0.44) TSHRCTSLCTSBCTSKBCHE
SCHEMBL30436176 0.87 BCHE (0.42) TSHRCTSLCTSBCTSKBCHE
SCHEMBL2510432 0.85 MEN1 (0.39) TSHRCTSLCTSBCTSKBCHE
SCHEMBL2571382 0.83 TSHR (0.43) TSHRCTSLCTSBCTSKIDO1
SCHEMBL30830814 0.82 TSHR (0.41) TSHRCTSLCTSBCTSKBCHE
SCHEMBL9171466 0.81 TSHR (0.44) TSHRCTSLCTSBCTSKIDO1
SCHEMBL7445879 0.79 TACR1 (0.47) TSHRCTSLCTSBCTSKPSEN1
SCHEMBL21574397 0.78 BCHE (0.65) BCHEPSEN1PSEN2APH1BNCSTN
SCHEMBL4752349 0.78 BCHE (0.65) BCHEPSEN1PSEN2APH1BNCSTN
SCHEMBL4184332 0.77 KDM4C (0.47) CTSLCTSBCTSKPSEN1PSEN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667786-B2 Encapsulating or filling composition for electronic devices and electronic apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-06 US disclosed
US-20230148213-A1 ALKANOLAMINE/AMINE-GRAFTED METAL-ORGANIC FRAMEWORK-BASED CARBON DIOXIDE ADSORBENT KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2023-05-11 US disclosed
US-20230148213-A1 ALKANOLAMINE/AMINE-GRAFTED METAL-ORGANIC FRAMEWORK-BASED CARBON DIOXIDE ADSORBENT KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2023-05-11 US disclosed
US-20230033621-A1 A POLYOL BLOCK COPOLYMER ECONIC TECHNOLOGIES LTD. (GB) 2023-02-02 US disclosed
US-10774180-B2 Catalysts ECONIC TECHNOLOGIES LTD. (GB) 2020-09-15 US disclosed
EP-3600610-A1 EXTRACTION OF CARBON DIOXIDE FROM GAS Ecole Polytechnique Federale de Lausanne (EPFL) (CH) 2020-02-05 EP disclosed
CN-109803656-A A kind of new compound of anti-candida albicans and its preparation method and application 华南农业大学 2019-05-24 CN disclosed
US-20190055352-A1 CATALYSTS ECONIC TECHNOLOGIES LTD. (GB) 2019-02-21 US disclosed
US-20170306079-A1 PHOSPHONIUM-BASED COMPOUND, EPOXY RESIN COMPOSITION CONTAINING SAME, SEMICONDUCTOR DEVICE MANUFACTURED USING SAME SAMSUNG SDI CO., LTD. (KR) 2017-10-26 US disclosed
CN-102875789-B A kind of polyether block copolymer and preparation method thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2015-10-07 CN disclosed
US-7851335-B2 acrylic polymer, epoxy resin, thermosetting resin, and as silicone a polysiloxane having aromatic side chain to improve compatibility with the epoxy resin and/or phenolic resin thermosetting agent, so it does not ooze out or cause outgas; stably connect a wire without contaminating a wire pad part LINTEC CORPORATION (JP) 2010-12-14 US disclosed
US-20100022515-A1 COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY IRM LLC (BM) 2010-01-28 US disclosed
US-20100022515-A1 COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY IRM LLC (BM) 2010-01-28 US disclosed
US-20090246915-A1 Adhesive Composition, Adhesive Sheet and Production Method of Semiconductor Device LINTEC CORPORATION (JP) 2009-10-01 US disclosed
US-20090246915-A1 Adhesive Composition, Adhesive Sheet and Production Method of Semiconductor Device LINTEC CORPORATION (JP) 2009-10-01 US disclosed
US-20090246913-A1 acrylic polymer, epoxy resin, thermosetting resin, and as silicone a polysiloxane having aromatic side chain to improve compatibility with the epoxy resin and/or phenolic resin thermosetting agent, so it does not ooze out or cause outgas; stably connect a wire without contaminating a wire pad part LINTEC CORPORATION (JP) 2009-10-01 US disclosed
US-20090246913-A1 acrylic polymer, epoxy resin, thermosetting resin, and as silicone a polysiloxane having aromatic side chain to improve compatibility with the epoxy resin and/or phenolic resin thermosetting agent, so it does not ooze out or cause outgas; stably connect a wire without contaminating a wire pad part LINTEC CORPORATION (JP) 2009-10-01 US disclosed
US-7022732-B2 6-substituted 2,3-dihydro-1,4-benzodioxine, 2-position substituted with carboxy, or (C1 C6)alkoxycarbonyl; diabetes, obesity; 6-[2-(R)-[2-(S)-hydroxy-3-(4-hydroxy-3-methanesulfonamido-phenoxy)propylamino]propyl]-2,3-dihydro-1,4-benzodioxine-2-(R)-carboxylic acid; B3 andrenergic receptor agonist NISSHIN PHARMA INC. (JP) 2006-04-04 US disclosed
US-20040235921-A1 Propanolamine derivative having 1, 4-Benzodioxane ring KYORIN PHARMACEUTICAL CO., LTD. (JP) 2004-11-25 US disclosed
EP-1426370-A1 PROPANOLAMINE DERIVATIVE HAVING 1,4 BENZODIOXANE RING Nisshin Pharma Inc. (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022515-A1 COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY GPR119, GCGR, GPR65 TSHR 926/4885CTSL 3872/4885CTSB 1393/4885
US-10774180-B2 Catalysts CA1, CA12, CA4 TSHR 4337/4885CTSL 795/4885CTSB 885/4885
US-20190055352-A1 CATALYSTS CA1, CA12, CA4 TSHR 4337/4885CTSL 795/4885CTSB 885/4885
US-20040235921-A1 Propanolamine derivative having 1, 4-Benzodioxane ring ADRA1D, ADRA1A, ADRB1 TSHR 1298/4885CTSL 3159/4885CTSB 4338/4885
US-20170306079-A1 PHOSPHONIUM-BASED COMPOUND, EPOXY RESIN COMPOSITION CONTAINING SAME, SEMICONDUCTOR DEVICE MANUFACTURED USING SAME PHOSPHO1, ASH2L, RER1 TSHR 4696/4885CTSL 4730/4885CTSB 4565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.