Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 16/20 | 0.40 |
| ▸ | TGM2 | P21980 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25718094 | 0.80 | BTK (0.41) | BTKTGM2EGFRKCNH2MAP2K7 | |
| SCHEMBL25718089 | 0.78 | BTK (0.41) | BTKTGM2EGFRKCNH2FGFR1 | |
| SCHEMBL25716847 | 0.77 | BTK (0.40) | BTKTGM2EGFRKCNH2 | |
| SCHEMBL25718087 | 0.76 | TGM2 (0.46) | BTKTGM2EGFRSRC | |
| SCHEMBL25718197 | 0.72 | TGM2 (0.39) | BTKTGM2 | |
| SCHEMBL25714928 | 0.71 | BTK (0.47) | BTKEGFR | |
| SCHEMBL25718091 | 0.70 | MAP2K7 (0.44) | BTKTGM2EGFRKCNH2MAP2K7 | |
| SCHEMBL25718199 | 0.68 | F10 (0.34) | BTKKCNH2FGFR1 | |
| SCHEMBL25718093 | 0.68 | TDP2 (0.33) | TGM2 | |
| SCHEMBL25714633 | 0.63 | HPGD (0.40) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |