Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 10/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25714929 | 0.79 | KIT (0.51) | BTKEGFRNPC1RAB9AMEN1 | |
| SCHEMBL25718087 | 0.76 | TGM2 (0.46) | BTKEGFR | |
| SCHEMBL25718093 | 0.75 | TDP2 (0.33) | F2 | |
| SCHEMBL25718089 | 0.73 | BTK (0.41) | BTKEGFRSMN1; SMN2FLT3 | |
| SCHEMBL25718094 | 0.72 | BTK (0.41) | BTKEGFRFLT3 | |
| SCHEMBL25716847 | 0.72 | BTK (0.40) | BTKEGFRF2 | |
| SCHEMBL27548451 | 0.72 | RAB9A (0.71) | NPC1RAB9AMEN1KMT2ACHRNB2 | |
| SCHEMBL25715112 | 0.71 | BTK (0.40) | BTKEGFR | |
| SCHEMBL25716915 | 0.71 | BTK (0.46) | BTKEGFRNPC1RAB9AMEN1 | |
| SCHEMBL25718197 | 0.69 | TGM2 (0.39) | BTKSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |