Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.34 |
| ▸ | F2 | P00734 | 5/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25718094 | 0.87 | BTK (0.41) | BTKKCNH2 | |
| SCHEMBL25716848 | 0.81 | BTK (0.38) | BTKJAK3 | |
| SCHEMBL25716849 | 0.80 | KIT (0.44) | MAPK14KDRJAK3FGFR1FGFR2 | |
| SCHEMBL25718091 | 0.78 | MAP2K7 (0.44) | BTKKCNH2 | |
| SCHEMBL25718196 | 0.75 | BTK (0.39) | BTKKCNH2GRM5FGFR4 | |
| SCHEMBL25718089 | 0.73 | BTK (0.41) | BTKKCNH2SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL25716910 | 0.73 | KDR (0.46) | BTKBRAFMAPK14KDRTNNI3K | |
| SCHEMBL25716989 | 0.72 | BTK (0.35) | BTKIGF1RCYP3A4CYP2D6FGFR1 | |
| SCHEMBL25716850 | 0.72 | BTK (0.41) | BTKKCNH2TP53 | |
| SCHEMBL30366502 | 0.69 | CYP3A4 (0.42) | F10BTKKDRGRM5P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |