Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 15/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715400 | 0.85 | JAK2 (0.39) | BTKJAK2JAK1TYK2JAK3 | |
| SCHEMBL25715151 | 0.84 | BTK (0.40) | BTKEGFRKCNH2ABL1 | |
| SCHEMBL25716316 | 0.77 | EPHB4 (0.40) | BTKEGFRKCNH2FGFR4 | |
| SCHEMBL25716378 | 0.75 | BTK (0.40) | BTKEGFRKCNH2FGFR4ABL1 | |
| SCHEMBL25715301 | 0.75 | KDR (0.38) | BTKEGFRFGFR4ABL1 | |
| SCHEMBL25718196 | 0.74 | BTK (0.39) | BTKEGFRKCNH2FGFR4 | |
| SCHEMBL25716455 | 0.74 | EGFR (0.39) | BTKEGFRKCNH2FGFR4ABL1 | |
| SCHEMBL25715149 | 0.74 | MAPK1 (0.36) | BTKEGFRKCNH2FGFR4 | |
| SCHEMBL25716441 | 0.73 | LCK (0.36) | BTKEGFRKCNH2FGFR4ABL1 | |
| SCHEMBL25715071 | 0.71 | BTK (0.49) | BTKEGFRKCNH2JAK2TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |