Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 8/20 | 0.35 |
| ▸ | ITK | Q08881 | 3/20 | 0.35 |
| ▸ | BTK | Q06187 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715151 | 0.87 | BTK (0.40) | EGFRBTKKCNH2SRCMAP2K7 | |
| SCHEMBL25716316 | 0.78 | EPHB4 (0.40) | EGFRBTKKCNH2FGFR4SRC | |
| SCHEMBL25716378 | 0.78 | BTK (0.40) | EGFRBTKKCNH2FGFR4SRC | |
| SCHEMBL25715301 | 0.77 | KDR (0.38) | MAPK1EGFRBTKFGFR4SRC | |
| SCHEMBL25716455 | 0.76 | EGFR (0.39) | MAPK1EGFRBTKKCNH2FGFR4 | |
| SCHEMBL25718196 | 0.75 | BTK (0.39) | EGFRITKBTKKCNH2FGFR4 | |
| SCHEMBL25716441 | 0.75 | LCK (0.36) | MAPK1EGFRBTKKCNH2FGFR4 | |
| SCHEMBL25715401 | 0.74 | BTK (0.36) | EGFRBTKKCNH2FGFR4 | |
| SCHEMBL25715211 | 0.74 | LCK (0.36) | MAPK1EGFRBTKKCNH2SRC | |
| SCHEMBL25715071 | 0.72 | BTK (0.49) | EGFRBTKKCNH2FGFR4SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |