SCHEMBL25720243

SCHEMBL25720243

CBc1cccc2c1-c1cc(Cl)ccc1C2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 4/20 0.40
DRD4 P21917 4/20 0.40
ITGA1 P56199 1/20 0.36
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
CYP1A2 P05177 1/20 0.35
CNR1 P21554 1/20 0.34
HPGD P15428 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CASP6 P55212 2/20 0.33
TYMS P04818 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
HSP90AA1 P07900 1/20 0.33
TDP2 O95551 1/20 0.32
METAP1 P53582 1/20 0.32
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25720295 0.91 HSP90AA1 (0.38) DRD2DRD4ITGA1CYP1A2CNR1
SCHEMBL23253870 0.83 METAP1 (0.39) HTR2AHTR2CHPGDCASP6TYMS
SCHEMBL25720352 0.76 DRD2 (0.40) DRD2DRD4ITGA1HTR2AHTR2C
SCHEMBL25720384 0.76 DRD2 (0.40) DRD2DRD4ITGA1HTR2AHTR2C
SCHEMBL25720288 0.75 DRD2 (0.40) DRD2DRD4ITGA1HTR2AHTR2C
SCHEMBL25720347 0.73 TSHR (0.37) DRD2HTR2AHTR2CCYP1A2L3MBTL1
SCHEMBL24329683 0.72 HSP90AA1 (0.55) DRD2DRD4ITGA1CYP1A2CNR1
SCHEMBL4896509 0.71 METAP1 (0.47) DRD2DRD4ITGA1HTR2AHTR2C
SCHEMBL29581704 0.71 METAP1 (0.47) DRD2DRD4ITGA1HTR2AHTR2C
SCHEMBL3785566 0.70 ITGA1 (0.54) DRD2DRD4ITGA1HTR2CCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4190779-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-06-07 EP disclosed