SCHEMBL25720288

SCHEMBL25720288

CSc1cccc2c1-c1cc(Cl)ccc1C2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 4/20 0.40
DRD4 P21917 4/20 0.40
HPGD P15428 3/20 0.37
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
ITGA1 P56199 1/20 0.36
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
CRHR1 P34998 1/20 0.35
CYP1A2 P05177 1/20 0.35
CNR1 P21554 1/20 0.34
MAPT P10636 3/20 0.34
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
LMNA P02545 2/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25720352 0.76 DRD2 (0.40) DRD2DRD4HPGDNPC1RAB9A
SCHEMBL25720384 0.76 DRD2 (0.40) DRD2DRD4HPGDNPC1RAB9A
SCHEMBL25720243 0.75 DRD2 (0.40) DRD2DRD4HPGDL3MBTL1ITGA1
SCHEMBL28641169 0.71 MAOA (0.55) KDM4EALDH1A1L3MBTL1CYP1A2MAPT
SCHEMBL4896509 0.71 METAP1 (0.47) DRD2DRD4ITGA1HTR2AHTR2C
SCHEMBL29581704 0.71 METAP1 (0.47) DRD2DRD4ITGA1HTR2AHTR2C
SCHEMBL3785566 0.70 ITGA1 (0.54) DRD2DRD4HPGDNPC1RAB9A
SCHEMBL28863723 0.68 METAP1 (0.43) DRD2DRD4ITGA1HTR2AHTR2C
SCHEMBL1921628 0.66 KDM4E (0.59) DRD2DRD4HPGDNPC1RAB9A
SCHEMBL24588651 0.66 RAB9A (0.56) HPGDNPC1RAB9ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4190779-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-06-07 EP disclosed