Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 2/20 | 0.54 |
| ▸ | PNP | P00491 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | KRAS | P01116 | 2/20 | 0.46 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.45 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17198456 | 0.87 | TGM2 (0.58) | POLBTGM2KRASFUT5P2RY2 | |
| SCHEMBL25723534 | 0.87 | RNASEL (0.47) | P2RY6NT5E | |
| SCHEMBL25712587 | 0.87 | RNASEL (0.44) | POLGP2RY6 | |
| SCHEMBL18503529 | 0.81 | TGM2 (0.58) | POLBTGM2KRASFUT5P2RY2 | |
| SCHEMBL26882941 | 0.80 | TAS1R3 (0.65) | TGM2KRASFUT5P2RY2P2RY4 | |
| SCHEMBL18512681 | 0.80 | ALDH1A1 (0.50) | POLGPNPPOLBTGM2KRAS | |
| SCHEMBL26883118 | 0.80 | TAS1R3 (0.65) | TGM2KRASFUT5P2RY2P2RY4 | |
| SCHEMBL26632575 | 0.80 | TAS1R3 (0.65) | TGM2KRASFUT5P2RY2P2RY4 | |
| SCHEMBL26632570 | 0.80 | TAS1R3 (0.65) | TGM2KRASFUT5P2RY2P2RY4 | |
| SCHEMBL31724981 | 0.79 | TAS1R3 (0.66) | TGM2KRASFUT5P2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131914-B1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2023-05-10 | — | — | EP | disclosed |