Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.60 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | APP | P05067 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TCF4 | P15884 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25721116 | 0.84 | MEN1 (0.53) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL24701466 | 0.83 | RAB9A (0.72) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL28472852 | 0.82 | NPC1 (0.52) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL6311016 | 0.75 | NPC1 (0.66) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL6311013 | 0.75 | NPC1 (0.66) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL29506637 | 0.74 | TCF4 (0.79) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL18712778 | 0.74 | TCF4 (0.79) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL6482368 | 0.70 | MAPT (0.46) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL6307248 | 0.69 | KDM4E (0.68) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL6307247 | 0.69 | KDM4E (0.68) | NPC1RAB9AMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104148-A1 | SMALL MOLECULE PROBE BINDING TO α-SYNUCLEIN AGGREGATE AND APPLICATION THEREOF | 复旦大学 | 2023-06-15 | — | — | WO | disclosed |