Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.45 |
| ▸ | TUBB | P07437 | 2/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25721073 | 0.84 | NPC1 (0.60) | MEN1KMT2AAPPMAPTNPC1 | |
| SCHEMBL24701466 | 0.81 | RAB9A (0.72) | MEN1KMT2ATLR9APPMAPT | |
| SCHEMBL28472852 | 0.80 | NPC1 (0.52) | MEN1KMT2AAPPMAPTNPC1 | |
| SCHEMBL28899811 | 0.78 | NPC1 (0.52) | MEN1KMT2ATLR9MAPTNPC1 | |
| SCHEMBL25721218 | 0.78 | KMT2A (0.48) | MEN1KMT2ATLR9MAPTNPC1 | |
| SCHEMBL14467557 | 0.73 | APP (0.68) | MEN1KMT2ATLR9APPMAPT | |
| SCHEMBL6368607 | 0.71 | MAOB (0.66) | APPMAPTMAOBTUBB4ATUBB | |
| SCHEMBL5494948 | 0.71 | MAOB (0.66) | APPMAPTMAOBTUBB4ATUBB | |
| SCHEMBL28473457 | 0.70 | MEN1 (0.50) | MEN1KMT2ATLR9MAPTNPC1 | |
| SCHEMBL30695515 | 0.70 | ALDH1A1 (0.58) | MEN1KMT2ATLR9MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104148-A1 | SMALL MOLECULE PROBE BINDING TO α-SYNUCLEIN AGGREGATE AND APPLICATION THEREOF | 复旦大学 | 2023-06-15 | — | — | WO | disclosed |