Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NAMPT | P43490 | 14/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | JUN | P05412 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13352236 | 0.86 | MMP1 (0.72) | NPC1RAB9ANAMPTHDAC1TRPV1 | |
| SCHEMBL25725288 | 0.86 | NAMPT (0.54) | NPC1RAB9ANAMPTKDM4EJUN | |
| SCHEMBL25722348 | 0.85 | NAMPT (0.56) | NPC1RAB9ANAMPTEGFR | |
| SCHEMBL25722346 | 0.85 | NAMPT (0.58) | NPC1RAB9ANAMPTKDM4EJUN | |
| SCHEMBL25722340 | 0.84 | HDAC1 (0.77) | NPC1RAB9ANAMPTHDAC1TRPV1 | |
| SCHEMBL30387813 | 0.83 | TRPM2 (0.64) | NPC1RAB9ANAMPTHDAC1TRPV1 | |
| SCHEMBL13320663 | 0.83 | TRPM2 (0.64) | NPC1RAB9ANAMPTHDAC1TRPV1 | |
| SCHEMBL4185775 | 0.83 | TRPM2 (0.64) | NPC1RAB9ANAMPTHDAC1TRPV1 | |
| SCHEMBL4185773 | 0.83 | TRPM2 (0.64) | NPC1RAB9ANAMPTHDAC1TRPV1 | |
| SCHEMBL10118164 | 0.81 | RAB9A (0.67) | NPC1RAB9ANAMPTKDM4EJUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202980-A1 | N-(2-Aminophenyl)-Prop-2-Enamide Derivatives, and Uses Thereof in the Treatment of Cancer | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2023-06-29 | — | — | US | disclosed |
| US-20230202980-A1 | N-(2-Aminophenyl)-Prop-2-Enamide Derivatives, and Uses Thereof in the Treatment of Cancer | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202980-A1 | N-(2-Aminophenyl)-Prop-2-Enamide Derivatives, and Uses Thereof in the Treatment of Cancer | SALL4, GLI2, GLI1 | NPC1 3763/4885RAB9A 2121/4885NAMPT 1176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.