Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 1/20 | 0.64 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.64 |
| ▸ | TRPA1 | O75762 | 6/20 | 0.62 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | NAMPT | P43490 | 3/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185773 | 1.00 | TRPM2 (0.64) | TRPM2LTB4RTRPA1TRPM8NPC1 | |
| SCHEMBL13320663 | 1.00 | TRPM2 (0.64) | TRPM2LTB4RTRPA1TRPM8NPC1 | |
| SCHEMBL4185775 | 1.00 | TRPM2 (0.64) | TRPM2LTB4RTRPA1TRPM8NPC1 | |
| SCHEMBL27866517 | 0.88 | BTK (0.56) | TRPM2LTB4RNPC1RAB9AMAPT | |
| SCHEMBL294402 | 0.86 | TRPM2 (0.83) | TRPM2LTB4RTRPA1TRPM8NPC1 | |
| SCHEMBL294403 | 0.86 | TRPM2 (0.83) | TRPM2LTB4RTRPA1TRPM8NPC1 | |
| SCHEMBL13320712 | 0.85 | TRPM2 (0.72) | TRPM2LTB4RTRPA1TRPM8NPC1 | |
| SCHEMBL25722340 | 0.83 | HDAC1 (0.77) | NPC1RAB9AMAPTNAMPTTRPV1 | |
| SCHEMBL13352236 | 0.83 | MMP1 (0.72) | NPC1RAB9AMAPTNAMPTTRPV1 | |
| SCHEMBL25722352 | 0.83 | NPC1 (0.59) | NPC1RAB9AMAPTNAMPTTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115978796-A | Synthesis method of substituted nitrogen-containing quinazolinone compound | 烟台宁远药业有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115978796-B | Synthesis method of substituted nitrogen-containing quinazolinone compound | 烟台宁远药业有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-115978796-A | Synthesis method of substituted nitrogen-containing quinazolinone compound | 烟台宁远药业有限公司 | 2023-04-18 | — | — | CN | disclosed |