SCHEMBL25726

SCHEMBL25726

[c]1ccc2oc3ccccc3c2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.46
MAOA P21397 5/20 0.46
KDM4E B2RXH2 4/20 0.46
ALDH1A1 P00352 4/20 0.46
HPGD P15428 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
GLA P06280 1/20 0.46
CYP3A4 P08684 1/20 0.46
PGAM1 P18669 1/20 0.46
CASP1 P29466 1/20 0.46
CASP7 P55210 1/20 0.46
HSD17B10 Q99714 1/20 0.46
AHR P35869 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 1/20 0.44
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5133924 0.89 KDM4E (0.33) MAPTMAOAKDM4EALDH1A1HPGD
SCHEMBL24762 0.87 MAPT (0.46) MAPTMAOAKDM4EALDH1A1HPGD
SCHEMBL1336718 0.84
SCHEMBL3367763 0.84 MAOA (0.67) MAPTMAOAKDM4EALDH1A1HPGD
SCHEMBL8113672 0.84 MAPT (0.34) MAPTMAOAKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL11564675 0.81 MAPT (0.65) MAPTMAOAKDM4EALDH1A1HPGD
SCHEMBL7829528 0.80 KMT2A (0.50) MAPTMAOAKDM4EALDH1A1HPGD
SCHEMBL21295967 0.79 MMP12 (0.40) MAPTKDM4EALDH1A1HPGDAHR
Dibenzofuran SCHEMBL28144928 0.78 MAPT (0.62) MAPTMAOAKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL9868133 0.78 MAPT (0.68) MAPTMAOAKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1795 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118284595-A Arylamine compound, organic electroluminescent element, and electronic device 保土谷化学工业株式会社 2024-07-02 CN claimed
CN-118201931-A Compound, composition, host material, and organic light-emitting element 九州有机光材股份有限公司 2024-06-14 CN claimed
CN-117980304-A Amine compound and organic electroluminescent element using same 保土谷化学工业株式会社 2024-05-03 CN claimed
EP-3749631-B1 TRIARYLMETHANE COMPOUNDS MITSUBISHI GAS CHEMICAL CO (JP) 2024-03-06 EP claimed
WO-2024010050-A1 AMINE COMPOUND, AND ORGANIC ELECTROLUMINESCENCE ELEMENT, ELECTRONIC EQUIPMENT, AND ELECTRONIC ELEMENT CONTAINING SAME 保土谷化学工業株式会社 2024-01-11 WO claimed
US-20230391704-A1 TRIARYLMETHANE COMPOUNDS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-12-07 US claimed
US-20230322673-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-10-12 US claimed
CN-116854599-A Tetraphenyl ethylene derivative and organic electroluminescent device comprising same 广东省大湾区华南理工大学聚集诱导发光高等研究院 2023-10-10 CN claimed
US-20230242568-A1 POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES MIRECA MEDICINES GMBH (DE) 2023-08-03 US claimed
WO-2023079993-A1 COMPOUND, COMPOSITION, HOST MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT 株式会社Kyulux 2023-05-11 WO claimed
WO-1996002517-A1 SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS DR. KARL THOMAE GMBH (DE) 1996-02-01 WO claimed
WO-1995026966-A1 CEPHALOSPORIN ANTIBIOTICS MICROCIDE PHARMACEUTICALS, INC. (US) 1995-10-12 WO claimed
EP-0658539-A1 Excitatory amino acid receptor antagonists ELI LILLY AND COMPANY (US) 1995-06-21 EP claimed
EP-0637303-A1 N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1995-02-08 EP claimed
EP-0607864-A2 Tricyclic condensed heterocyclic compounds for the treatment of senile dementic Takeda Chemical Industries, Ltd. (JP) 1994-07-27 EP claimed
WO-1993022302-A1 N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1993-11-11 WO claimed
EP-0335636-A1 Antiviral compounds SYNPHAR LABORATORIES INC. (CA) 1989-10-04 EP claimed
EP-0194764-B1 PESTICIDAL COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1989-07-12 EP claimed
EP-0194764-A1 Pesticidal compounds THE WELLCOME FOUNDATION LIMITED (GB) 1986-09-17 EP claimed
EP-0000346-A1 Quinoxaline compounds, process for their manufacture and their use as brighteners for organic materials, and the materials brightened therewith BAYER AG (DE) 1979-01-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242568-A1 POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES PRKG1, PRKG2, PRKAG3 MAPT 4120/4885MAOA 1533/4885KDM4E 598/4885
US-20230322673-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE L1CAM, CCNL2, CTNND1 MAPT 2501/4885MAOA 2406/4885KDM4E 825/4885
US-20230391704-A1 TRIARYLMETHANE COMPOUNDS CBR3, HAX1, HRH3 MAPT 4486/4885MAOA 3067/4885KDM4E 1561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.