Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21357740 | 0.75 | AR (0.42) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL14360705 | 0.74 | MAPT (0.50) | ALDH1A1MAPTLMNABACE1MEN1 | |
| SCHEMBL1544992 | 0.73 | ALDH1A1 (0.47) | ALDH1A1CYP2A6MAPTLMNABACE1 | |
| SCHEMBL29589106 | 0.73 | MAPT (0.57) | ALDH1A1MAPTLMNABACE1MEN1 | |
| SCHEMBL3761395 | 0.71 | LMNA (0.66) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL17375980 | 0.70 | HRH3 (0.49) | ALDH1A1MAPTBACE1MEN1KMT2A | |
| SCHEMBL6014116 | 0.70 | TRIM24 (0.50) | ALDH1A1CYP2A6LMNAMEN1KMT2A | |
| SCHEMBL15962920 | 0.68 | MAOB (0.45) | ALDH1A1CYP2A6MAPTLMNAHPGD | |
| SCHEMBL19214399 | 0.67 | ALDH1A1 (0.86) | ALDH1A1CYP2A6MAPTLMNACYP3A4 | |
| SCHEMBL6351 | 0.67 | ALDH1A1 (0.86) | ALDH1A1CYP2A6MAPTLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160207908-A1 | BROAD SPECTRUM ANTIVIRAL AND ANTIPARASITIC AGENTS | NIH-DEITR | 2016-07-21 | — | — | US | disclosed |
| US-9139575-B2 | Broad spectrum antiviral and antiparasitic agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-09-22 | — | — | US | disclosed |
| US-20130028966-A1 | Broad Spectrum Antiviral and Antiparasitic Agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-01-31 | — | — | US | disclosed |
| WO-2011130419-A2 | BROAD SPECTRUM ANTIVIRAL AND ANTIPARASITIC AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-10-20 | — | — | WO | disclosed |
| WO-2009148004-A1 | NOVEL COMPOUND AND PHARMACEUTICAL APPLICATION OF SAME | 株式会社 三和化学研究所 (JP) | 2009-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207908-A1 | BROAD SPECTRUM ANTIVIRAL AND ANTIPARASITIC AGENTS | MAVS, EIF2AK2, ZC3HAV1 | ALDH1A1 1660/4885CYP2A6 779/4885MAPT 2628/4885 |
| US-20130028966-A1 | Broad Spectrum Antiviral and Antiparasitic Agents | MAVS, EIF2AK2, ZC3HAV1 | ALDH1A1 1660/4885CYP2A6 779/4885MAPT 2628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.