Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25278785 | 0.87 | ALDH1A1 (0.47) | ALDH1A1HTTKCNA5GAAMAPK1 | |
| SCHEMBL25642109 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KCNA5PKMRAB9ALMNA | |
| SCHEMBL25273247 | 0.78 | SMN1; SMN2 (0.53) | ALDH1A1HTTGAASMN1; SMN2NPC1 | |
| SCHEMBL19834817 | 0.78 | GPR119 (0.49) | ALDH1A1NPC1RAB9ALMNACASP7 | |
| SCHEMBL25278094 | 0.78 | SMN1; SMN2 (0.53) | ALDH1A1HTTGAASMN1; SMN2NPC1 | |
| SCHEMBL19834770 | 0.77 | HDAC3 (0.52) | ALDH1A1KCNA5SMN1; SMN2RAB9ALMNA | |
| SCHEMBL25235675 | 0.75 | SMN1; SMN2 (0.48) | ALDH1A1HTTGAASMN1; SMN2NPC1 | |
| SCHEMBL22032226 | 0.75 | GPR119 (0.68) | MMP13GPR119 | |
| SCHEMBL31746376 | 0.75 | GPR119 (0.68) | MMP13GPR119 | |
| SCHEMBL30020119 | 0.74 | GPR119 (0.48) | ALDH1A1NPC1RAB9ALMNAGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192651-A1 | Pyrrolidine Derivative and Use Thereof | WANG, ZHEMING (CN) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192651-A1 | Pyrrolidine Derivative and Use Thereof | NAMPT, NAPRT, NNMT | ALDH1A1 1525/4885HTT 630/4885KCNA5 2331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.