Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405879 | 0.82 | CTSK (0.53) | SMN1; SMN2KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL3399391 | 0.77 | ALDH1A1 (0.47) | SMN1; SMN2KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL13650781 | 0.71 | NUDT1 (0.61) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL27961208 | 0.68 | MAP2K7 (0.40) | SMN1; SMN2KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL12068673 | 0.68 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL7930954 | 0.67 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL13828994 | 0.67 | NUDT1 (0.46) | SMN1; SMN2KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL3403384 | 0.66 | CYP3A4 (0.43) | CTSKCTSSKCNH2 | |
| SCHEMBL3402052 | 0.66 | CTSK (0.53) | SMN1; SMN2MAPTCTSKCTSSKCNH2 | |
| SCHEMBL3425396 | 0.66 | ALDH1A1 (0.45) | SMN1; SMN2KMT2AALDH1A1MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |