Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9908372 | 0.83 | PARP1 (0.53) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL840084 | 0.80 | MAPK1 (0.60) | LOXL2LMNAPOLBSMN1; SMN2SCN9A | |
| SCHEMBL15747506 | 0.79 | ALDH1A1 (0.50) | LOXL2SCN9ASCN10AKDM4EALDH1A1 | |
| SCHEMBL12924077 | 0.78 | PDE10A (0.55) | LOXL2POLBRAB9ASCN9ASCN10A | |
| SCHEMBL12561176 | 0.78 | PLK1 (0.55) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL24956517 | 0.77 | LOXL2 (0.48) | LOXL2SCN9ASCN10AGABRA1 | |
| SCHEMBL840724 | 0.77 | LOXL2 (0.50) | LOXL2SMN1; SMN2NPC1RAB9ASCN9A | |
| SCHEMBL4475119 | 0.76 | LMNA (0.64) | LMNAPOLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27308715 | 0.76 | MAPT (0.49) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14524662 | 0.76 | L3MBTL1 (0.44) | MAPTSMN1; SMN2KDM4ETDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109521-A1 | PARP INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 凯复(苏州)生物医药有限公司 | 2023-06-22 | — | — | WO | disclosed |