Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 8/20 | 0.61 |
| ▸ | GSK3B | P49841 | 4/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178186 | 0.89 | RORB (0.54) | RORBGSK3BADORA2AADORA1CCNA2 | |
| SCHEMBL257613 | 0.86 | RORB (0.52) | RORBADORA2AADORA1ALDH1A1RORC | |
| SCHEMBL10092883 | 0.85 | RORB (0.67) | RORBADORA2AADORA1CCNA2CDK2 | |
| SCHEMBL257615 | 0.84 | RORB (0.72) | RORBADORA2ACCNA2CDK2ALDH1A1 | |
| SCHEMBL257393 | 0.82 | RORB (0.60) | RORBADORA2AADORA1CCNA2CDK2 | |
| SCHEMBL257203 | 0.81 | RORB (0.67) | RORBALDH1A1RORCMYCWDR5 | |
| SCHEMBL257432 | 0.80 | RORB (0.74) | RORBADORA2AADORA1CCNA2CDK2 | |
| SCHEMBL11274884 | 0.79 | MYC (0.51) | RORBALDH1A1RORCMYCWDR5 | |
| SCHEMBL2489836 | 0.79 | MYC (0.51) | RORBCDK2ALDH1A1RORCMYC | |
| SCHEMBL30395217 | 0.79 | MYC (0.51) | RORBALDH1A1RORCMYCWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |