SCHEMBL25742012

SCHEMBL25742012

CCn1cc(C(=O)C(CO)NC)c2ccc(F)cc21

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 5/20 0.42
CNR2 P34972 4/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NR4A2 P43354 1/20 0.40
HTR3A P46098 3/20 0.38
HAT1 O14929 2/20 0.37
EP300 Q09472 2/20 0.37
SERPINE1 P05121 1/20 0.37
LMNA P02545 2/20 0.37
PDE10A Q9Y233 3/20 0.36
POLB P06746 1/20 0.36
HPGD P15428 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25742077 0.92 CNR1 (0.43) CNR1CNR2MEN1KMT2ANR4A2
SCHEMBL25742032 0.91 HTR3A (0.44) CNR1CNR2NR4A2HTR3AHAT1
SCHEMBL25742015 0.89 CNR1 (0.41) CNR1CNR2MEN1KMT2ANR4A2
SCHEMBL25742020 0.86 HAT1 (0.44) CNR1CNR2MEN1KMT2ANR4A2
SCHEMBL25742011 0.85 IDO1 (0.46) CNR1CNR2MEN1KMT2ANR4A2
SCHEMBL25742052 0.85 CNR1 (0.43) CNR1CNR2MEN1KMT2ANR4A2
SCHEMBL25742083 0.83 CNR1 (0.42) CNR1CNR2MEN1KMT2ANR4A2
SCHEMBL25742002 0.83 CNR1 (0.43) CNR1CNR2MEN1KMT2ANR4A2
SCHEMBL25742089 0.82 HTR3A (0.45) CNR1CNR2NR4A2HTR3AHAT1
SCHEMBL25742035 0.80 HTR3A (0.42) CNR1CNR2NR4A2HTR3AHAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257347-A1 ADVANTAGEOUS TRYPTAMINE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT TACTOGEN INC (US) 2023-08-17 US disclosed
US-20230257347-A1 ADVANTAGEOUS TRYPTAMINE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT TACTOGEN INC (US) 2023-08-17 US disclosed
WO-2023107715-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2023-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257347-A1 ADVANTAGEOUS TRYPTAMINE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT HTR6, TPH2, TPH1 CNR1 118/4885CNR2 47/4885MEN1 219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.