SCHEMBL25747597

SCHEMBL25747597

CN(C)CCc1c[nH]c2cc(F)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR1A P08908 12/20 1.00
▸ HTR2A P28223 8/20 0.61
▸ HTR2C P28335 8/20 0.61
▸ HTR2B P41595 7/20 0.61
▸ HTR6 P50406 5/20 0.61
▸ HTR1D P28221 4/20 0.61
▸ HTR1B P28222 4/20 0.61
▸ HTR1E P28566 3/20 0.61
▸ HTR7 P34969 3/20 0.61
▸ HTR5A P47898 3/20 0.61
▸ DRD1 P21728 1/20 0.61
▸ ADORA2A P29274 1/20 0.61
▸ ADORA2B P29275 1/20 0.61
▸ DRD3 P35462 1/20 0.61
▸ MPO P05164 2/20 0.54
▸ SLC6A4 P31645 2/20 0.50
▸ HTR1F P30939 3/20 0.46
▸ HTR3E A5X5Y0 2/20 0.45
▸ HTR3B O95264 2/20 0.45
▸ HTR3A P46098 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25748759 0.85 HTR1A (0.74) HTR1AHTR2AHTR2CHTR2BHTR6
SCHEMBL25241728 0.84 HTR1A (0.72) HTR1AHTR2AHTR2CHTR2BHTR6
SCHEMBL25383625 0.82 HTR1A (0.70) HTR1AHTR2AHTR2CHTR2BHTR6
SCHEMBL25379806 0.82 HTR1A (0.70) HTR1AHTR2AHTR2CHTR2BHTR6
SCHEMBL26202981 0.81 HTR1A (0.68) HTR1AHTR2AHTR2CHTR2BHTR6
SCHEMBL25381818 0.80 HTR1A (0.67) HTR1AHTR2AHTR2CHTR2BHTR6
SCHEMBL12559104 0.80 HTR1A (0.67) HTR1AHTR2AHTR2CHTR2BHTR6
SCHEMBL31708139 0.79 HTR1A (0.66) HTR1AHTR2AHTR2CHTR2BHTR6
SCHEMBL24420531 0.78 HTR1A (0.64) HTR1AHTR2AHTR2CHTR2BHTR6
SCHEMBL31708192 0.77 HTR1A (0.63) HTR1AHTR2AHTR6HTR7MPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250090554-A1 A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION MYND LIFE SCIENCES INC (CA) 2025-03-20 — — US disclosed
US-20250059217-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF PREPARATION THEREOF BRIGHT MINDS BIOSCIENCES INC. (CA) 2025-02-20 — — US disclosed
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS SYNAPTIVE THERAPEUTICS, LLC 2024-11-07 — — US disclosed
CN-117897376-A Heterocyclic compounds and process for preparing same 光明智慧生物科学公司 2024-04-16 — — CN disclosed
EP-4347561-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF PREPARATION THEREOF Bright Minds Biosciences Inc. (CA) 2024-04-10 — — EP disclosed
US-20230405026-A1 A Method of Treating Depression by Immune Modulation MYND LIFE SCIENCES INC (CA) 2023-12-21 — — US disclosed
WO-2023115166-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 — — WO disclosed
WO-2022246554-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF PREPARATION THEREOF BRIGHT MINDS BIOSCIENCES INC. (CA) 2022-12-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS HTR1B, HTR2B, PNMT HTR1A 8/4885HTR2A 5/4885HTR2C 4/4885
US-20250059217-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF PREPARATION THEREOF OPRL1, OPRK1, CNR2 HTR1A 306/4885HTR2A 413/4885HTR2C 79/4885
US-20230405026-A1 A Method of Treating Depression by Immune Modulation ABCF1, ABCF2, ABCB4 HTR1A 507/4885HTR2A 377/4885HTR2C 1196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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