SCHEMBL25747780

SCHEMBL25747780

CN(C)CCc1c[nH]c2cc3c(cc12)OCC3

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 11/20 0.86
HTR2C P28335 9/20 0.86
HTR1A P08908 10/20 0.69
HTR2A P28223 9/20 0.69
HTR1B P28222 8/20 0.69
HTR2B P41595 7/20 0.69
HTR6 P50406 5/20 0.69
HTR3E A5X5Y0 4/20 0.69
HTR3B O95264 4/20 0.69
HTR1E P28566 4/20 0.69
HTR1F P30939 4/20 0.69
HTR7 P34969 4/20 0.69
HTR3A P46098 4/20 0.69
HTR5A P47898 4/20 0.69
HTR4 Q13639 4/20 0.69
HTR3D Q70Z44 4/20 0.69
HTR3C Q8WXA8 4/20 0.69
MPO P05164 1/20 0.49
SLC6A4 P31645 1/20 0.49
CYP1A2 P05177 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25747785 0.82 HTR2C (0.60) HTR1DHTR2CHTR1AHTR2AHTR1B
SCHEMBL30249043 0.82 HTR1D (1.00) HTR1DHTR2CHTR1AHTR2AHTR1B
SCHEMBL20970981 0.82 HTR1D (1.00) HTR1DHTR2CHTR1AHTR2AHTR1B
SCHEMBL15701965 0.72 HTR1D (0.63) HTR1DHTR2CHTR1AHTR2AHTR1B
SCHEMBL517481 0.71 HTR1D (0.61) HTR1DHTR2CHTR1AHTR2AHTR1B
SCHEMBL30483734 0.71 HTR1A (0.74) HTR1DHTR2CHTR1AHTR2AHTR1B
SCHEMBL25747532 0.71 HTR1A (0.74) HTR1DHTR2CHTR1AHTR2AHTR1B
SCHEMBL30483743 0.71 HTR2C (0.59) HTR1DHTR2CHTR1AHTR2AHTR1B
SCHEMBL30483747 0.71 HTR2C (0.86) HTR1DHTR2CHTR1AHTR2AHTR1B
SCHEMBL30483741 0.71 HTR2C (0.59) HTR1DHTR2CHTR1AHTR2AHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250101038-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-03-27 US disclosed
EP-4452937-A1 COMPOUNDS Psylo Pty Ltd (AU) 2024-10-30 EP disclosed
CN-118715204-A Compounds of formula (I) 普赛洛私人有限公司 2024-09-27 CN disclosed
WO-2023115166-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 WO disclosed
WO-2023115166-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250101038-A1 COMPOUNDS NLN, SLC18A2, PYGB HTR1D 344/4885HTR2C 23/4885HTR1A 185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.