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SCHEMBL25751314

SCHEMBL25751314

CCCCC(C)(CC)N1C(=O)C2C3CCC(C4C(=O)N(c5ccc(Oc6ccc(-c7ccc(Oc8ccc(C(C)(CC)CCC)cc8)cc7)cc6)cc5)C(=O)C34)C2C1=O

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.32
▸ HTT P42858 2/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ ALDH1A1 P00352 3/20 0.31
▸ MAPT P10636 2/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ THRB P10828 1/20 0.30
▸ GAA P10253 1/20 0.30
▸ PABPC1 P11940 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25751300 0.80 MAPT (0.30) HTTALDH1A1MAPT
SCHEMBL21215977 0.75 KMT2A (0.33) SMN1; SMN2ALDH1A1HSD17B10
SCHEMBL21064097 0.72 ALDH1A1 (0.33) LMNAHTTSMN1; SMN2ALDH1A1MAPT
SCHEMBL21215699 0.71 KMT2A (0.35) HTTSMN1; SMN2ALDH1A1MAPT
SCHEMBL21215696 0.70 SMN1; SMN2 (0.38) LMNAHTTSMN1; SMN2ALDH1A1
SCHEMBL25751305 0.69 NPC1 (0.39) MAPT
SCHEMBL25751324 0.68 KMT2A (0.33) LMNAHTTSMN1; SMN2ALDH1A1MAPT
SCHEMBL20706537 0.68 ALDH1A1 (0.38) HTTALDH1A1MAPT
SCHEMBL13433539 0.67 MEN1 (0.31) ALDH1A1
SCHEMBL13855428 0.66 LMNA (0.46) LMNAHTTSMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230205031-A1 ELECTROCHROMIC COMPOSITION, ELECTROCHROMIC LAYER AND ELECTROCHROMIC DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-29 — — US disclosed