SCHEMBL25751324

SCHEMBL25751324

CCC(CC)c1ccc(Oc2ccc(N3C(=O)C4C5CCC(C4C3=O)C3C(=O)N(C(C)(C)CC)C(=O)C53)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.33
ATM Q13315 1/20 0.33
LMNA P02545 4/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
ALDH1A1 P00352 3/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
MEN1 O00255 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
HTT P42858 2/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25751305 0.79 NPC1 (0.39) KMT2AMAPTPOLB
SCHEMBL25751300 0.71 MAPT (0.30) ALDH1A1L3MBTL1HTTTP53MAPT
SCHEMBL14494737 0.70 KMT2A (0.37) KMT2AATMSMN1; SMN2ALDH1A1CYP3A4
SCHEMBL25751314 0.68 LMNA (0.32) LMNASMN1; SMN2ALDH1A1HTTMAPT
SCHEMBL13400440 0.68 LMNA (0.48) KMT2ALMNASMN1; SMN2ALDH1A1MEN1
SCHEMBL12086250 0.67 NPBWR1 (0.38) KMT2ALMNASMN1; SMN2ALDH1A1MEN1
SCHEMBL13855428 0.65 LMNA (0.46) KMT2ALMNASMN1; SMN2ALDH1A1MEN1
SCHEMBL25751079 0.62 LMNA (0.40) KMT2ALMNASMN1; SMN2ALDH1A1MEN1
SCHEMBL8852859 0.62 MGLL (0.51) KMT2AATMLMNASMN1; SMN2ALDH1A1
SCHEMBL5922653 0.62 L3MBTL1 (0.50) KMT2ASMN1; SMN2ALDH1A1MEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230205031-A1 ELECTROCHROMIC COMPOSITION, ELECTROCHROMIC LAYER AND ELECTROCHROMIC DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-29 US disclosed