SCHEMBL25751649

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25751645	0.94	SMN1; SMN2 (0.42)	MEN1TP53KMT2ASMN1; SMN2USP2
	SCHEMBL25751644	0.87	ALDH1A1 (0.32)	TP53SMN1; SMN2ALDH1A1CA12CA1
	SCHEMBL25751710	0.85	ALDH1A1 (0.35)	MEN1TP53KMT2ASMN1; SMN2ALDH1A1
	SCHEMBL25751651	0.85	SMN1; SMN2 (0.37)	MEN1TP53KMT2ASMN1; SMN2USP2
	SCHEMBL25751707	0.83	MEN1 (0.31)	MEN1KMT2ASMN1; SMN2ALDH1A1
	SCHEMBL25751702	0.78	—	—
	SCHEMBL25751654	0.78	CYP1A2 (0.37)	KMT2AALDH1A1LMNAPHGDHMGLL
	SCHEMBL24051517	0.77	MEN1 (0.45)	MEN1TP53KMT2ASMN1; SMN2USP2
	SCHEMBL12562452	0.75	SMN1; SMN2 (0.45)	MEN1TP53KMT2ASMN1; SMN2USP2
	SCHEMBL25753750	0.72	SMN1; SMN2 (0.43)	MEN1TP53KMT2ASMN1; SMN2PDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.