SCHEMBL12562452

SCHEMBL12562452

C/C(=N\C(C)(C)C)N1CCOCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.45
USP2 O75604 1/20 0.41
ALDH1A1 P00352 2/20 0.38
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA9 Q16790 3/20 0.37
CA2 P00918 2/20 0.37
LMNA P02545 1/20 0.36
FAAH O00519 1/20 0.35
PHGDH O43175 1/20 0.35
ALDH2 P05091 1/20 0.35
PDK1 Q15118 1/20 0.35
PDK2 Q15119 1/20 0.35
PDK3 Q15120 1/20 0.35
MGLL Q99685 1/20 0.35
MEN1 O00255 1/20 0.34
TP53 P04637 1/20 0.34
KMT2A Q03164 1/20 0.34
HTT P42858 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18763332 0.81 RECQL (0.33) SMN1; SMN2USP2MEN1KMT2AHTT
SCHEMBL25751645 0.80 SMN1; SMN2 (0.42) SMN1; SMN2USP2ALDH1A1CA12CA1
SCHEMBL12562454 0.79 ALDH1A1 (0.36) SMN1; SMN2ALDH1A1LMNATP53KMT2A
SCHEMBL12562451 0.77 KMT2A (0.36) SMN1; SMN2ALDH1A1CA12CA1CA9
SCHEMBL18651769 0.77 CTSS (0.35)
SCHEMBL25751649 0.75 MEN1 (0.41) SMN1; SMN2USP2ALDH1A1CA12CA1
SCHEMBL17236510 0.75 SMN1; SMN2 (0.50) SMN1; SMN2USP2ALDH1A1CA12CA1
SCHEMBL1105467 0.75 SMN1; SMN2 (0.50) SMN1; SMN2USP2ALDH1A1CA12CA1
SCHEMBL19861950 0.75 SMN1; SMN2 (0.50) SMN1; SMN2USP2ALDH1A1CA12CA1
SCHEMBL27062090 0.74 MAPT (0.42) SMN1; SMN2USP2ALDH1A1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11185853-B2 Catalysts for polycarbonate production SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2021-11-30 US disclosed
US-10662211-B2 Catalysts and methods for polymer synthesis Saurdi Aramco Technologies Company (SA) 2020-05-26 US disclosed
US-20190193062-A1 CATALYSTS FOR POLYCARBONATE PRODUCTION ARAMCO PERFORMANCE MATERIALS LLC 2019-06-27 US disclosed
US-20180179242-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. 2018-06-28 US disclosed
US-20180179242-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. 2018-06-28 US disclosed
US-9951096-B2 Catalysts and methods for polymer synthesis SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2018-04-24 US disclosed
US-9856349-B2 Catalysts and methods for polymer synthesis SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2018-01-02 US disclosed
US-20170183369-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-06-29 US disclosed
US-20170107241-A1 SALEN COMPLEXES WITH DIANIONIC COUNTERIONS NOVOMER, INC. (US) 2017-04-20 US disclosed
US-20170080409-A1 CATALYSTS FOR EPOXIDE CARBONYLATION NOVOMER, INC. (US) 2017-03-23 US disclosed
US-8956989-B2 Catalysts and methods for polymer synthesis NOVOMER, INC. (US) 2015-02-17 US disclosed
US-8951930-B2 Catalysts and methods for polymer synthesis NOVOMER, INC. (US) 2015-02-10 US disclosed
US-8946109-B2 Catalysts and methods for polymer synthesis NOVOMER, INC. (US) 2015-02-03 US disclosed
US-20140336354-A1 SALEN COMPLEXES WITH DIANIONIC COUNTERIONS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2014-11-13 US disclosed
US-8633123-B2 Catalysts and methods for polymer synthesis NOVOMER, INC. (US) 2014-01-21 US disclosed
US-20130172524-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2013-07-04 US disclosed
US-20130144032-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2013-06-06 US disclosed
US-20130144033-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2013-06-06 US disclosed
US-20130144031-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2013-06-06 US disclosed
US-20110152497-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170107241-A1 SALEN COMPLEXES WITH DIANIONIC COUNTERIONS NCLN, POLN, NCL SMN1; SMN2 949/4885USP2 4553/4885ALDH1A1 3519/4885
US-10662211-B2 Catalysts and methods for polymer synthesis PPOX, COASY, SOD1 SMN1; SMN2 4314/4885USP2 2588/4885ALDH1A1 2255/4885
US-20140336354-A1 SALEN COMPLEXES WITH DIANIONIC COUNTERIONS NCLN, POLN, NCL SMN1; SMN2 949/4885USP2 4553/4885ALDH1A1 3519/4885
US-20130144032-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 SMN1; SMN2 4314/4885USP2 2588/4885ALDH1A1 2255/4885
US-20180179242-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 SMN1; SMN2 4314/4885USP2 2588/4885ALDH1A1 2255/4885
US-20130144033-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 SMN1; SMN2 4314/4885USP2 2588/4885ALDH1A1 2255/4885
US-20170183369-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 SMN1; SMN2 4314/4885USP2 2588/4885ALDH1A1 2255/4885
US-20110152497-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 SMN1; SMN2 4314/4885USP2 2588/4885ALDH1A1 2255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.