SCHEMBL25751805

SCHEMBL25751805

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4oc(-c5cccc(-c6ccc7c(c6)c6ccccc6n7-c6ccc7ocnc7c6)c5)nc4c3)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ HPSE Q9Y251 10/20 0.40
▸ DYRK1A Q13627 1/20 0.37
▸ UTRN P46939 1/20 0.36
▸ CASP3 P42574 2/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ SENP7 Q9BQF6 2/20 0.35
▸ SENP6 Q9GZR1 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ NPC1 O15118 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ SENP8 Q96LD8 1/20 0.35
▸ S1PR1 P21453 3/20 0.35
▸ S1PR3 Q99500 2/20 0.35
▸ FAAH O00519 1/20 0.34
▸ GAA P10253 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ HDAC6 Q9UBN7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25751911 0.94 VSIR (0.36) HPSEDYRK1AUTRNCASP3SMN1; SMN2
SCHEMBL25751813 0.92 HPSE (0.44) HPSEUTRNCASP3SMN1; SMN2SENP7
SCHEMBL25459469 0.89 HPSE (0.47) HPSEUTRNCASP3SMN1; SMN2SENP7
SCHEMBL25751763 0.88 HPSE (0.49) HPSEUTRNCASP3SMN1; SMN2SENP7
SCHEMBL25459466 0.88 HPSE (0.47) HPSEUTRNCASP3SMN1; SMN2SENP7
SCHEMBL25751921 0.87 HPSE (0.41) HPSEUTRNCASP3SMN1; SMN2SENP7
SCHEMBL27049522 0.86 HPSE (0.46) HPSECASP3SMN1; SMN2SENP7SENP6
SCHEMBL25459462 0.86 NPC1 (0.43) HPSEUTRNCASP3SMN1; SMN2SENP7
SCHEMBL25751811 0.85 HPSE (0.39) HPSEUTRNCASP3SMN1; SMN2SENP7
SCHEMBL25459477 0.85 SMN1; SMN2 (0.47) HPSECASP3SMN1; SMN2SENP7SENP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230217814-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-07-06 — — US disclosed
US-20230217814-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-07-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230217814-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME AOX1, XDH, PPOX HPSE 3938/4885DYRK1A 3954/4885UTRN 3277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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